WebAnswer: Compounds which have the same molecular formula but differ in their arrangement of atoms in space are called isomers and the property is called isomerism. For example, cisplatin. It has two isomeric forms, the cis form and the trans form. The figure below shows cis and trans platin (left- cis platin, right- trans platin). WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
Stereoisomers: Geometric Isomers in cis-platin
WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … WebIn comparison with cisplatin, they show comparable cytotoxic potency against cisplatin-sensitive human cancer cell lines, cis-[Pt(2-abt)(2)Cl(2)]·H(2)O performing substantially higher activity against cisplatin-resistant cell lines. ... Isomerism Male Molecular Structure Organoplatinum Compounds / chemical synthesis ... how to write a blacklist letter
Synthesis of cis- and trans- Diamminedichloroplatinum(II)
WebJun 12, 2024 · Isomers are extremely important in the development of pharmaceuticals, as typically, only one isomer of a particular molecule will exert the desired effect. For example, only one isomer for ibuprofen will … WebJul 25, 2024 · In geometrical isomer nomenclature, the prefix cis- and trans- are used to identify which side of the double bond the similar atoms are found. The cis- prefix is from the Latin meaning "on this side". In this case, the chlorine atoms are on the same side of the carbon-carbon double bond. This isomer is called cis-1,2-dichloroethene. WebAug 15, 2024 · CIS/TRANS isomers have different biological properties. Cis-platin has clinical importance in the treatment of ovarian and testicular cancers. The biological mechanism of the drug's action was long suspected to involve binding of the platinum by … how to write a blessing